<p>This article describes the 100 days campaign at the Sultan Bin Abdulaziz Humanitarian City Rehabilitation and Medical Center, which aimed for the hospital to be 100% free of hospital-acquired pressure ulcers (HAPUs) during the 100-day campaign period. The campaign involved the whole organisation with 17 inpatient units participating. The centre’s practices regarding the management of patients’ skin, which had been developed over the previous four years, were retained during the period, but there was an additional multi-faceted prevention awareness campaign targeting healthcare professionals, patients and their carers. Fifteen of the 17 inpatient units (88%) maintained a zero HAPU percentage during the 100 days, reducing the monthly average rate by 73% from 1.35% to 0.36%.</p>